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	Provedor de dados Nature Precedings (1) Autor Ashutosh Kumar (1) Geeta Negi (1) Shyam S. Sharma (1) Palavra-chave Cancer (1) Pharmacology (1) Tipo do documento Manuscript (1) Ano 2011 (1) País United Kingdom (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Adopting Nrf2 and NF-κB from cancer: Is there any role of the duo in diabetes? Nature Precedings Geeta Negi; Ashutosh Kumar; Shyam S. Sharma. Oxidative stress and inflammation are two well-recognized events occurring in normal cells during cancer chemotherapy. Several antioxidant and anti-inflammatory agents have therefore been tried as rational and effective strategies for chemoprotection. Elaborate studies on antioxidants and anti-inflammatory agents in various experimental models of cancer revealed that these agents act by modulating the expression and/or activity of the transcription factors nuclear factor erythroid 2-related factor 2 (Nrf2) and nuclear factor-kappa B (NF-κB). Nrf2 is considered the main sentinel of antioxidant defense as it induces many antioxidant and phase 2 enzymes in response to stressful conditions. Likewise, NF-κB is considered as a denominator of... Tipo: Manuscript Palavras-chave: Cancer; Pharmacology. Ano: 2011 URL: http://precedings.nature.com/documents/6581/version/1 Registros recuperados: 1 Primeira ... 1 ... Última

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